Active Ingredient: Sildenafil Citrate
Treatment: Erectile Dysfunction
Country of Manufacture: Czech Republic (Multinational)
Vigrande Package Image
Review and Description
Vigrande 25 mg is a regular sildenafil formulation, which is capable of producing the same results as Viagra by Pfizer in sufferers of erectile dysfunction and impotence. Film-coated tablets of Vigrande are available on the market. The manufacturer doesn’t produce 25mg tablets; it favors higher doses. These tablets wouldn’t be effective ED remedies without Sildenafil citrate, which is the main active ingredient. Smooth muscle relaxation and blood vessel expansion in the penis would not be possible otherwise. To make that possible, Sildenafil citrate must first curb the activity of phospodiesterase-5 in the cavernosum, which is responsible for cyclic guanosine monophosphate disintegration. Thus cGMP ceases to disintegrate due to Sildenafil presence and its concentration in the region becomes greater. Greater cGMP concentration is necessary for smooth muscle relaxation and blood vessel expansion. That makes subsequent erections firmer.
Czech Republic-based Zentiva, a Sanofi-Aventis subsidiary, produces Vigrande. This subsidiary serves as the center of Sanofi’s R&D as well as generic pharmaceuticals production. The larger company laid the foundation for the current relationship between these two companies in a 2006 acquisition. The deal was finalized 3 years later. Zentiva’s pharmaceutical business has ties to a 15th-century Bohemian pharmacy, which was one of the earliest in the region. Prague, which was part of that region, was the site of Black Eagle’s production plant in 1930. Sixty-three years after, Black Eagle became Leciva. In 1998, the company changed its name to Zentiva – a move that was accompanied by a shift in focus to branded generics. Sanofi-Aventis started branding its generics with Zentiva in 2011. That is why Vigrande, which formerly bore the Turkish Eczacibasi brand, now bears Zentiva.
The Internet does not have any customer reviews for Vigrande 25 milligrams. This is obviously due to what we earlier alluded to: The manufacturer doesn’t produce 25 milligrams tablets of Vigrande. If you find out that the higher doses of this medication are too strong for your erectile dysfunction treatment, you can always get a pill-cutter to get the desired dose. If you don’t fancy a pill-cutter, there are alternative erectile dysfunction therapies you can use instead. We’ll tell you about one such alternative later on. We do believe, however, that Zentiva’s track record of achievement both in the European and international market is a good enough basis to give the higher doses a try. Since the acquisition of Slovakopharma and the launch of the Zentiva corporate brand in 2003, the company’s reach has expanded to over eight hundred million people. Its wide product catalog comprises over four hundred molecules including products for Pain, CNS, Gastrointestinal, Cardiovascular, Respiratory, Urology, and erectile dysfunction.
Pricing and Dosage
Vigrande Sildenafil is only synthesized and packed in blisters containing four 50 milligrams and 100 milligrams tablets coated in film. Based on the foregoing, there is also no pricing information or dosage information for Vigrande 25 milligrams tablets. All you will find on the Internet is pricing and dosage information for the fifty milligrams and one hundred milligrams tablets. The pricing for these doses is higher than that of most generic sildenafil medications but still far from being as costly as Brand Viagra. 30 tablets of that medication have a unit price of 24.83 US dollars on the average if you are shopping online.
This sildenafil preparation should be taken in the same manner as its generic equivalents: once a day.
How to Buy Vigrande Online
Vigrande appears to be a relatively unpopular erectile dysfunction therapy and so the 100 milligrams and 50 milligrams tablets are available only on a select few pharmacy websites. Some of the most reliable vendors on our TOP recommended Pharmacies List, like the two below, however, do not stock this medication. Instead, they stock more popular generics like Fildena.
For customers looking for a 25 millgrams sildenafil dose, Fildena 25 milligrams is available on Pharmacymall.net. 270 pills of this formulation cost 195.75 US dollars. This store has no policy that compels its customers to submit recent prescriptions by their physicians and when you surpass $200 you are guaranteed of free shipping on your order.
You won’t get either the 25 milligrams dose or the 50 milligrams dose on Canadapharmacy24h.com. The only available dose is 100 milligrams. 270 tablets of this preparation cost 185.07 US dollars. This store has no policy that compels its customers to submit recent prescriptions by their physicians either. Surpassing $200 guarantees you free shipping.
How to Use
Vigrande and Fildena are both oral therapies that should be taken by mouth. While administering this drug, patients are advised to refrain from consuming food that might interfere with the drug’s efficacy. Alcoholic beverages, for example, have been identified as a hindrance to the speed of absorption of Sildenafil. Grapefruit also falls into this class of substances. Store free of moisture and under 30 degrees Celsius.
The following adverse effects are seen often in ED patients who use Sildenafil: Facial Flushing, Dyspepsia, Coughing, Nausea, Headaches, Temporary Color Blindness, and Hives. The following adverse effects are infrequent in ED patients who use Sildenafil: Paresthesia, Hypercarnitinemia, Hyperuricaemia, Priapism, Asthenia, Exfoliative Dermatitis, Edema of the Face and Limbs, Stevens Johnson’s Syndrome, Hypotension, and Reduced Visual Acuity.
Conclusion with Rating
Vigrande is a regular sildenafil formulation, which is capable of producing the same results as Viagra by Pfizer in sufferers of erectile dysfunction and impotence. Vigrande Sildenafil is only synthesized and packed in blisters containing four 50 milligrams and 100 milligrams tablets coated in film. Czech Republic-based Zentiva, a Sanofi-Aventis subsidiary, produces Vigrande in Prague. This subsidiary serves as the center of Sanofi’s R&D as well as generic pharmaceuticals production. We did not find any credible customer testimonials for this product on the Internet and it is unavailable on many reputable online pharmacy stores. For this reason, we are giving these tablets three out of five stars.